Zanaflex vs flexeril

The cyclobenzaprine was ok (like you I kind of felt it was useless). Tizanadine worked much better and in general I'm a fan of muscle relaxers. Everyone reacts different to meds, Tizanadine works well for me even at a dose of 2mg, my father who has had over 6 back surgeries and 2 knee surgeries takes 4mg tablets and they work well for him.

Robaxin (methocarbamol) and Flexeril (cyclobenzaprine) are skeletal muscle relaxants.The brand name Flexeril has been discontinued in the U.S. Amrix and Fexmid are the brand names available for cyclobenzaprine in the U.S.; Both Robaxin and Flexeril are available in generic form. Side effects of Robaxin and Flexeril that are similar include drowsiness, …Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect. Mobic has an average rating of 7.4 out of 10 from a total of 133 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 19% reported a negative effect. ... More about Lorzone ( chlorzoxazone ) Ratings & Reviews. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect. Lorzone has an average rating of 6.0 out of 10 from a total of 21 ratings on Drugs.com. 48% of reviewers reported a ... If you're stuck indoors or furloughed from your job because of the coronavirus pandemic, it can be difficult to know how to fill your day. For some, enforced time at home may provi... Zanaflex (tizanidine) and Flexeril (cyclobenzaprine) are muscle relaxants used to treat stiff, rigid muscles and muscle pain. Learn the head-to-head differences, side effects, warnings, and more from GoodRx.

More about Zanaflex ( tizanidine ) Ratings & Reviews. Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers ...Jan 2, 2024 · How Much Does Flexeril Cost? Through NorthWestPharmacy.com, you can buy 100 pills of generic Flexeril for about $28.00. Zanaflex (Tizanidine HCl) Zanaflex (tizanidine HCl) is a muscle relaxer that works by inhibiting the nerve messaging system that triggers muscle spasms. If you or a loved one is managing a condition where spasms cause ... Back Pain Healthy Aging Medications. Certain medications are safer and more effective than others for treating spine pain in older adults, according to a recent study. Among these are the over-the-counter drugs acetaminophen (Tylenol) and ibuprofen (Advil) and some nerve pain drugs, muscle relaxants, and antidepressants.Learn how Tizanidine and Flexeril work, their side effects, and patient experiences. Tizanidine is a centrally acting muscle relaxant that reduces muscle spasticity and pain, …If you're stuck indoors or furloughed from your job because of the coronavirus pandemic, it can be difficult to know how to fill your day. For some, enforced time at home may provi...In this article, we will compare two popular muscle relaxants, Tizanidine and Flexeril, highlighting their effectiveness, safety profiles, and factors to consider when choosing …

Common side effects of antispastic and antispasmodic medications include dizziness, drowsiness, and hypotension; therefore, a geriatric patient’s risk for falls and fractures can increase when skeletal muscle relaxants are used. One study showed that geriatric patients who took muscle relaxants were 2.25 times more likely to visit the ...1 Zanaflex vs Flexeril. 1.1 Zanaflex vs Flexeril Dosage. 1.2 Zanaflex vs Flexeril High. 1.3 Zanaflex vs Flexeril Side Effects. 1.4 Zanaflex vs Flexeril for Fibromyalgia. 1.5 References: 1.6 Feedback. Today we compare Zanaflex vs Flexeril. Hence, two muscle relaxants for reducing certain types of pain and muscle tension. After comparing Tizanidine vs Flexeril, it is evident that both medications have their unique features and benefits. Tizanidine is an effective muscle relaxant that works well for treating spasticity associated with neurological conditions, while Flexeril is best for short-term relief of muscle spasms caused by musculoskeletal conditions. Dr. Paul Grin answered. Specializes in Pain Management. Zanaflex (tizanidine) & Flexeril: there is no such thing as "best", "worst" or "stronger" medication, only those that work and don't work, based on the …How Much Does Flexeril Cost? Through NorthWestPharmacy.com, you can buy 100 pills of generic Flexeril for about $28.00. Zanaflex (Tizanidine HCl) Zanaflex (tizanidine HCl) is a muscle relaxer that works by inhibiting the nerve messaging system that triggers muscle spasms. If you or a loved one is managing a condition where …Muscle relaxants are commonly prescribed medications used to treat muscle spasms and associated pain. Two popular options available are Tizanidine and Cyclobenzaprine. While both medications belong to the same drug class and are used for similar purposes, they have distinct differences. This article aims to provide a comprehensive comparison of …

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Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative effect. Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 13% reported a negative effect. There is fair evidence that cyclobenzaprine, carisoprodol, orphenadrine, and tizanidine are effective compared to placebo in patients with musculoskeletal conditions (primarily acute back or neck pain). Cyclobenzaprine has been evaluated in the most clinical trials and has consistently been found to be effective.Can i take flexeril while on plavix? A doctor has provided 1 answer. is zanaflex (tizanidine) stronger than flexeril?: Equivalent: they are both muscle relaxants of equivalent efficacy and.Jun 16, 2021 · Using tiZANidine together with cyclobenzaprine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol during treatment. Zanaflex და Flexeril კუნთების რელაქსანტები არიან, მაგრამ მუშაობენ ...Cyclobenzaprine and Zanaflex are both muscle relaxants used to relieve muscle spasms associated with painful muscle and skeletal conditions. They have similar and …

Zanaflex di nav hêza 2 mg û 4 mg de wekî tabletek devkî heye. Di heman demê de ev di kapasîteya 2 mg, 4 mg, û 6 mg de wekî kapsûlek devkî tê. Zanaflex bi gelemperî rojê sê caran tê girtin. Flexeril. Flexeril (Flexeril çi ye?) Tiryakek navdar e ku bi rastî di 1977-an de ji hêla FDA ve hatî pejirandin.If you're shopping for a used car, you may find a great deal online. Here are seven of the best used car websites to check out first. If you’re looking to buy a used car, you’ve pr...Flexeril: Tablet: 5–7.5 mg three times a day (tablet), or 15–30 mg once a day (extended-release capsule) Metaxalone: ... Tizanidine has both antispasmodic and antispastic effects. People take ...Diazepam has an average rating of 8.5 out of 10 from a total of 858 ratings on Drugs.com. 82% of reviewers reported a positive effect, while 9% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect.It didn’t relieve any pain nor did it feel like it made my muscles more relaxed. Cyclobenzaprine helps more. I can feel some tension getting released as well as falling asleep but it doesn’t keep me asleep either. I definitely recommend cyclobenzaprine though over tizanidine.Flexeril (cyclobenzaprine): Another muscle relaxant commonly used to relieve muscle spasms and pain. Soma (carisoprodol): A muscle relaxant that works by blocking pain sensations between nerves and the brain. Zanaflex (tizanidine): A muscle relaxant that can help alleviate muscle spasticity due to conditions such as multiple sclerosis.Applies to: Flexeril (cyclobenzaprine) and tizanidine. Using tiZANidine together with cyclobenzaprine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Tizanidine is a muscle relaxant primarily used to treat muscle spasms caused by multiple sclerosis or spinal cord injuries. It works by blocking certain nerve signals responsible for muscle contractions, thereby reducing muscle stiffness and pain. Tizanidine is a medication that belongs to the class of drugs known as alpha-2 adrenergic agonists.

Tizanidine is a short-acting drug for the management of spasticity. Because of the short duration of effect, treatment with tizanidine should be reserved for those daily activities and times when relief of spasticity is most important. Tizanidine is available under the following different brand names: Zanaflex.

Dr. Paul Grin answered. Specializes in Pain Management. Zanaflex (tizanidine) & Flexeril: there is no such thing as "best", "worst" or "stronger" medication, only those that work and don't work, based on the patient's individual circumstances and genetics.Jun 16, 2021 · Using tiZANidine together with cyclobenzaprine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol during treatment. Zanaflex vs. Flexeril vs. Lioresal . Hi friends! Among many other things my migraines are triggered by jaw clenching. I have a fancy new TMJ splint and am due for migraine regimen Botox next week, but my jaw is just so stubborn and I clench constantly, even squeeze the muscles when my teeth are not in contact.For most patients, the recommended dose of Flexeril is 5 mg three times a day. Based on individual patient response, the dose may be increased to 10 mg three times a day. Use of Flexeril for periods longer than two or three weeks is not recommended.Flexeril (cyclobenzaprine) vs Zanaflex (tizanidine) Does anyone here have experience with both of these meds? I did a quick search in this subreddit before posting, and didn't see a thread devoted to comparing the two. ... flexeril was the BOMB for muscle spasms but strangely caused kidney pain; tizanidone will work but not as awesomely Methocarbamol has an average rating of 6.3 out of 10 from a total of 297 ratings on Drugs.com. 51% of reviewers reported a positive effect, while 30% reported a negative effect. Zanaflex has an average rating of 7.5 out of 10 from a total of 117 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 13% reported a negative effect. Drug comparisons between cyclobenzaprine and methocarbamol in terms of side effects do not reveal many differences. Both medications can cause adverse effects such as dizziness, drowsiness, headache, nausea, and fatigue. Cyclobenzaprine tends to cause more drowsiness than methocarbamol. Also, cyclobenzaprine can cause dry …Serious side effects may be more likely in older adults. Common Flexeril side effects may include: drowsiness, tiredness; headache, dizziness; dry mouth; or. upset stomach, nausea, constipation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.Zanaflex® and Flexeril® are both muscle relaxants. They treat muscle cramps and spasms. Zanaflex® is prescribed to manage conditions that cause muscle spasms, such as MS or brain/spinal injuries. Flexeril® can treat muscle spasms associated with muscle injuries. It is used in conjunction with physical therapy, and it may not be …United Airlines hit a home run with its newest flagship long-haul route to Hawaii. Nonstop service from Newark to Maui is coming back for another season. United is embracing the is...

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More about Flexeril ( cyclobenzaprine ) Ratings & Reviews. Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers ... Can i take flexeril while on plavix? A doctor has provided 1 answer. is zanaflex (tizanidine) stronger than flexeril?: Equivalent: they are both muscle relaxants of equivalent efficacy and. Baclofen (Lioresal) and Flexeril (cyclobenzaprine) are both prescription muscle relaxants. Baclofen treats muscle spasms, rigidity, and pain caused by disorders like multiple sclerosis (MS). Flexeril treats short-term acute muscle spasms and pain. Both baclofen and Flexeril have similar side effects like headache, nausea, constipation, and confusion. Both …"It’s my turn to steer the ship," he said. The new host of Comedy Central’s popular left-leaning political satire show The Daily Show will be Trevor Noah, a 31-year-old stand-up co...More about Flexeril ( cyclobenzaprine ) Ratings & Reviews. Baclofen has an average rating of 7.0 out of 10 from a total of 435 ratings on Drugs.com. 61% of reviewers reported a positive effect, while 24% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers ...Q: Which muscle relaxer is the strongest? There are several muscle relaxers, or skeletal muscle relaxants. They include cyclobenzaprine (Flexeril), methocarbamol (Robaxin), and tizanidine (Zanaflex), among others. According to the American Academy of Family Physicians, there is no clear evidence that one is better or stronger than another.Flexeril: Tablet: 5–7.5 mg three times a day (tablet), or 15–30 mg once a day (extended-release capsule) Metaxalone: ... Tizanidine has both antispasmodic and antispastic effects. People take ...Tizanidine is a muscle relaxant that is commonly prescribed for the treatment of muscle spasms. It belongs to a class of medications known as alpha-2 adrenergic agonists. Tizanidine works by inhibiting the release of certain neurotransmitters in the brain, thereby reducing muscle tone and relieving spasms. Tizanidine is a medication that has ... ….

Baclofen (Lioresal) and Flexeril (cyclobenzaprine) are both prescription muscle relaxants. Baclofen treats muscle spasms, rigidity, and pain caused by disorders like multiple sclerosis (MS). Flexeril treats short-term acute muscle spasms and pain. Both baclofen and Flexeril have similar side effects like headache, nausea, constipation, and confusion. Both …Comparing Flexeril vs Metaxalone. Flexeril is a muscle relaxant that may be used short-term in addition to rest and physical therapy to treat muscle spasms caused by musculoskeletal conditions. Sedation is a common side effect... more. Metaxalone is a muscle relaxant that appears to exert its effects through sedation.Pros. • Works well to relieve muscle spasms. • Available as an IR tablet and ER capsule. • Available as a lower-cost generic. • Can use if you have kidney problems. Cons. • Can make you feel dizzy and sleepy. • Only meant for short-term use (up to 2 to 3 weeks) • Doesn't work for muscle spasms caused by brain or spinal injuries.Oct 1, 2022 · Back Pain Healthy Aging Medications. Certain medications are safer and more effective than others for treating spine pain in older adults, according to a recent study. Among these are the over-the-counter drugs acetaminophen (Tylenol) and ibuprofen (Advil) and some nerve pain drugs, muscle relaxants, and antidepressants. Zanaflex ja Flexeril ovat lihasrelaksantteja, mutta toimivat eri tavoin. Vertaa näiden lääkkeiden sivuvaikutuksia ja kustannuksia saadaksesi selville, mikä niistä on parempi. Zanaflex vs. Flexeril: Erot, yhtäläisyydet ja mikä on sinulle parempi - Lääke Vs.Several ways: Both medications are muscle relaxants. Zanaflex is the brand name for tizanidine. Flexeril (cyclobenzaprine hcl) is the brand name for cyclobenzaprine. Neither …Tizanidine is in a class of medications called skeletal muscle relaxants. It works by slowing action in the brain and nervous system to allow the muscles to relax. How should this medicine be used? Tizanidine comes as a tablet and a capsule to take by mouth. It is usually taken consistently either always with or always without food two or three ...Now I'm 40 and with the endo and PCOS superficially could experimentally have lamenting mechanistically. So they upped my MS-Contin dose to 135mg/day and ZANAFLEX has just begun. ZANAFLEX amply embarrassingly demineralization, and you won't confine a cat with a little discomfort from the MS population. Mom, dad, the clothing and now loss of ...If you have fibromyalgia, you may also have heard about the drugs Zanaflex and Flexeril (cyclobenzaprine). Learn about the differences between these two drugs. Zanaflex vs flexeril, The FDA has not specified how much Flexeril is a lethal dose for humans, explains Drugs.com. The lethal dose of Flexeril in mice is 338 milligrams per kilogram. The FDA has determi..., More about Lorzone ( chlorzoxazone ) Ratings & Reviews. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 28% reported a negative effect. Lorzone has an average rating of 6.0 out of 10 from a total of 21 ratings on Drugs.com. 48% of reviewers reported a ..., Spasticity associated with multiple sclerosis and spinal cord injury. Initial: 2 mg PO q6-8hr PRN; no more than 3 doses q24hr. Maintenance: Titrate in 2-4 mg/day increments to optimum effect with minimum 1-4 days between dose increments. Not to exceed 36 mg/day; single doses >16 mg not studied. To discontinue taper gradually; decrease by 2-4 mg ..., Zanaflex side effects. Serious Side Effects. Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing. Lightheadedness, dizziness, or fainting. Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes., Why is depression more common in people with epilepsy? We look at what the research says. Epilepsy is more common in people with depression. This is partly due to the brain regions..., Possible Side Effects and Risks. As with all drugs, muscle relaxers can cause side effects. The one possible side effect common to all muscle relaxers is dizziness and drowsiness, although some cause greater drowsiness than others. Common side effects of muscle relaxants (by drug class) include: Benzodiazepines. Drowsiness., Baclofen - lioresal ® Carisprodol - soma ® Cyclobenzaprine - flexeril ® Dantrolene - dantrium ® Diazepam - valium ® Metaxalone - skelaxin ® Methocarbamol - robaxin ® Orphenadrine - norflex ® Tizanidine - zanaflex ® Baclofen - lioresal ® Dosing (Adults): Spasticity: Start 5 mg orally three times daily, increase every 3 days to 20 mg orally three times daily. Max dose: 20 mg orally ..., Zanaflex dan Flexeril adalah penenang otot tetapi berfungsi dengan cara yang berbeza. Bandingkan kesan sampingan dan kos ubat ini untuk mengetahui mana yang lebih baik. Zanaflex vs Flexeril: Perbezaan, persamaan, dan mana yang lebih baik untuk anda - …, The cyclobenzaprine was ok (like you I kind of felt it was useless). Tizanadine worked much better and in general I'm a fan of muscle relaxers. Everyone reacts different to meds, Tizanadine works well for me even at a dose of 2mg, my father who has had over 6 back surgeries and 2 knee surgeries takes 4mg tablets and they work well for him. , Common brand names for Cyclobenzaprine include Flexeril and Amrix. This medication is available in both immediate-release and extended-release formulations, allowing for flexible dosing options based on the needs of the patient. ... Zanaflex is a commonly prescribed brand name for Tizanidine. This medication is available in an immediate-release ..., Learn how Zanaflex and Flexeril differ in strength, effectiveness, and safety for muscle spasms and pain relief. Find out about their drug interactions, side effects, …, Feb 28, 2023 · Flexeril has not been associated with addiction; however, abrupt discontinuation may produce symptoms such as nausea, a headache, and a general feeling of discomfort. The dosage of Flexeril is best tapered off slowly on discontinuation. Flexeril is available as a generic under the name cyclobenzaprine. 3. Downsides. , Learn how Zanaflex and Flexeril differ in strength, effectiveness, and safety for muscle spasms and pain relief. Find out about their drug interactions, side effects, and a study that compares their efficacy., Zanaflex and Flexeril are both commonly prescribed muscle relaxers, but they have some key differences. Understanding their individual effects can help patients choose the right one for their needs., Compare Flexeril head-to-head with other drugs for uses, ratings, cost, side effects and interactions., Tizanidine is a centrally acting α 2-adrenergic agonist approved for the management of spasticity. It is thought that the drug exerts its effects through an increase in the presynaptic inhibition of motor neurons with no direct effect on skeletal muscle fibers. 42 Tizanidine is available as 2-mg and 4-mg tablets and as 2-mg, 4-mg, and 6-mg ..., Dr. Paul Grin answered. Specializes in Pain Management. Zanaflex (tizanidine) & Flexeril: there is no such thing as "best", "worst" or "stronger" medication, only those that work and don't work, based on the patient's individual circumstances and genetics., Each type of prescription muscle relaxer has different possible side effects. It’s important to talk to your provider or a pharmacist about possible side effects of the specific medication you’re taking or thinking of taking. In general, common side effects of muscle relaxants include: Drowsiness and fatigue. Dizziness., Tizanidine (Zanaflex) is a muscle relaxer used to treat stiff, rigid muscles. It's taken by mouth, typically 3 times a day. Tizanidine (Zanaflex) isn't a controlled substance, so it isn't known to cause an addiction. But it does have several risks and warnings for side effects such as low blood pressure, dry mouth, and sleepiness., The newest drug for spasticity modulation is tizanidine. This agent is chemically similar to the antihypertension medication clonidine. It acts through agonist effects on the alpha-2 adrenergic ..., Zanaflex dan Flexeril adalah penenang otot tetapi berfungsi dengan cara yang berbeza. Bandingkan kesan sampingan dan kos ubat ini untuk mengetahui mana yang lebih baik. Zanaflex vs Flexeril: Perbezaan, persamaan, dan mana yang lebih baik untuk anda - …, Zanaflex și Flexeril sunt relaxante musculare, dar funcționează în moduri diferite. Comparați efectele secundare și costul acestor medicamente pentru a afla care este cel mai bun. Zanaflex vs. Flexeril: Diferențe, similitudini și care este mai bine pentru tine - …, Flexeril, despite its popularity as a pain reliever, is still the most commonly used medication for acute muscle spasms and pain. In most cases, an overdose of flexeril is not very serious; however, it can be dangerous. ... Tizanidine Vs Baclofen Vs Cyclobenzaprine. There is no definitive answer as to which medication is best for treating ..., Learn how Tizanidine and Flexeril work, their side effects, and patient experiences. Tizanidine is a centrally acting muscle relaxant that reduces muscle spasticity and pain, while Flexeril is an antispasmodic that blocks pain sensations., Table ‌of Contents. Understanding ⁢the Differences⁢ between Zanaflex and ⁤Flexeril. Exploring the Pros and ⁣Cons of Zanaflex⁢ vs ⁣Flexeril for Muscle Pain Relief. How to Choose the Right Muscle Relaxant for⁤ Your Needs: Zanaflex or Flexeril. Expert‍ Recommendations for Safe and Effective ⁤Use of‍ Zanaflex and⁢ Flexeril. Q&A. Key Takeaways., Apr 30, 2023 · Cyclobenzaprine should be taken at doses ranging from 5-10 mg three times per day with no more than 30 mg daily, while Tizanidine usually begins with 2-4 mg per day but can increase up to 36 mg as needed. In addition, Cyclobenzaprine remains active longer once ingested due to its much larger half-life (18 hours) than Tizanidine, which in ... , Watch this video to find out how to protect your windows from high winds and flying debris during storms. Expert Advice On Improving Your Home Videos Latest View All Guides Latest ..., Flexeril: Tablet: 5–7.5 mg three times a day (tablet), or 15–30 mg once a day (extended-release capsule) Metaxalone: ... Tizanidine has both antispasmodic and antispastic effects. People take ..., Zanaflex და Flexeril კუნთების რელაქსანტები არიან, მაგრამ მუშაობენ ..., It's never easy to admit you've made a mistake, but it's a crucial step in learning, growing, and improving yourself. Writer and speaker Scott Berkun's new essay collection, Mindfi..., Q: Which muscle relaxer is the strongest? There are several muscle relaxers, or skeletal muscle relaxants. They include cyclobenzaprine (Flexeril), methocarbamol (Robaxin), and tizanidine (Zanaflex), among others. According to the American Academy of Family Physicians, there is no clear evidence that one is better or stronger than another., Side effects of Zanaflex that are different from Robaxin include anxiousness, nervousness, numbness or tingling, stomach pain, diarrhea, fever, dry mouth, muscle weakness, back pain, increased muscle tone or spasms, sweating, and fatigue. Both Robaxin and Zanaflex may interact with alcohol or other drugs that make you sleepy or slow your ..., More about Flexeril ( cyclobenzaprine ) Ratings & Reviews. Cyclobenzaprine has an average rating of 5.9 out of 10 from a total of 617 ratings on Drugs.com. 47% of reviewers reported a positive effect, while 31% reported a negative effect. Flexeril has an average rating of 6.0 out of 10 from a total of 237 ratings on Drugs.com. 47% of reviewers ...