Maternit21 vs natera

Maternit21 vs nuchal with vanishing twin pregnancy . Which test is preferred for a vanishing twin pregnancy where the one twin didn’t make it sometime between 9 weeks-11 weeks? (It measured at 6.5 weeks size at the 9 week ultrasound and there was no heartbeat. ... False Positive NIPT Natera Results DiGeorges Syndrome.

Since its introduction in 2011, noninvasive prenatal testing (NIPT) has spread rapidly around the world. It carries numerous benefits but also raises challenges, often related to sociocultural, legal, and economic contexts. This article describes the implementation of NIPT in nine countries, each with its own unique characteristics: Australia, Canada, China and Hong Kong, India, Israel ...For example, MaterniT21 PLUS looks at microdeletions and other abnormalities in a dozen specific chromosomes. MaterniT GENOME screens and detects up to 30% more genetic abnormalities than any other NIPT. It also detects chromosomal aneuploidies missed by other NIPTs, providing earlier awareness and more proactive pregnancy management options.July 2012. I had the MaterniT21 test after getting some sketchy results from the intergrated screening. They told me that there was a 1:15 chance that the baby had Downs Syndrome. I had a Level II ultrasound done at 16 weeks and there were luckily no marker's on the baby.The case number is 21-CIV-06237. The plaintiffs, identified as A.P. and B.P., have filed a complaint for damages and demand for a jury trial against Natera, Inc., a corporation, and Does One through Ten, inclusive. The complaint includes various claims, such as negligent failure to recall, strict products liability, negligence, conversion ...Like most noninvasive prenatal screenings (NIPSs/NIPTs), MaterniT GENOME can tell you if you screen positive or negative for trisomies 21 (Down syndrome), 18 (Edwards syndrome), and 13 (Patau syndrome), and if you're having a boy or a girl. But it can also find other chromosomal changes that may go undiagnosed at birth.

MaterniT21 Gender Determination for Twins. I am currently 12 weeks with di/di Twins. Yesterday afternoon I got results of MaterniT21. My OB’s office previously told me that it would only tell me if it was both girls or at least one boy. Yesterday, they called me and told me, based on my MaterniT21 results, that I am having two boys.My Natera NIPT came back in December 2022 with No Result for Monosomy X - Atypical Findings on the X Chromosome. I decided to opt out if the amnio because ultrasounds were perfect and baby is here! My beautiful, healthy little girl was born on 6/20/23. I do want to have her tested for mosaicism or micro deletions/duplications.The Panorama test, developed by Natera, is another prenatal test that analyzes cell-free DNA in the mother’s blood to detect chromosomal abnormalities. It is similar to the MaterniT21 and Harmony tests in its ability to identify trisomy 21, trisomy 18, and trisomy 13.MaterniT21 PLUS vs Natera Panorama - comparison. No Result / Low Fetal Fraction. If you are in the US and you have the choice between NIPT by MaterniT21 (Labcorp) or Natera Panorama, I would choose MaterniT21 any day. I wanted to share my experience in case this helps anybody choose. For uninteresting reasons, I had both tests done.and evaluation of invasive vs. non-invasive ... companies (e.g., Natera, BGI, Illumina). Three ... Non-invasive Prenatal Testing (NIPT) Market. (BambniTest, Harmony ... 12.5w - NIPT extended panel (MaterniT21) came back high risk for microdeletion on chromosome 15 (prader willi/Angelman syndrome) 13w - genetic counselor gave our estimated risk about .37% so we were hopeful it was a false positive. 16 w - amnio, no complications. 16.5w - we were told not enough cells were collected in sample and would need to ...

‡Natera evaluated in silico the overlap in coverage between WES-derived mutational signatures and commercially available ctDNA assays. Note that these performance estimates assume 100% mutation detection in covered genes, which may not occur in practice depending on VAF, input quantities, base-level sensitivity, etc.MaterniT21. Labcorp6–9. Harmony. Roche4,5. Illumina ... Provides a result >99% of the time, versus a. 10 ... Visit natera.com to learn more about how Natera ...Results included those from Sequenom's MaterniT21 and SafeT21 tests, BGI's NIFTY, Illumina's Verifi, Natera's Panorama, and Ariosa's Harmony. A single result came from LabCorp's Integrated Genetics InformaSeq test. For 13 of the cases, karyotyping of cells from amniocentesis or chorionic villus sampling revealed mosaicism.My OB said I had to wait until after 10 weeks for Natera nipt. We did the genetic carrier screening at 8 weeks, because that’s just looking at what mom is a carrier for, but I was told we had to wait for NIPT to ensure the fraction of fetal DNA was high enough to produce results; too early can give inconclusives and need to be redrawn. 1.The NIPT/cfDNA Performance Caclulator is a tool to quickly and easily understand the positive predictive value of a prenatal test given the condition, maternal age, specificity of the test, and sensitivity of the test. This web based PPV calculator was made by Sound Information Services LLC in a combined effort with the National Society of Genetic Counselors (NSGC) and the Perinatal Quality ...Maternal serum screening, also called "triple screen" or "quad screen", is a noninvasive screening test that measures specific substances in the mother's blood. This test is most commonly used to detect Down syndrome (trisomy 21), Edward's syndrome (trisomy 18), and open neural tube defects like spina bifida.

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Trisomy13 nipt high risk. Hello, My wife took panorama test, first time we had low fraction dna, and high risk for all 3 trisomies, second time low risk for trisomy12 and 18 but high risk for trisomy13. 68/100 She took triple test and all tests are normal, ultrasound is normal at 16 weeks but we worry a lot.Two of the tests currently on the market (MaterniT21™ by Sequenom and Verifi™ by Verinata) use massive parallel (“next generation”) sequencing of random DNA fragments …There are currently two main NIPT tests available in the UK: Harmony Test and Panorama Test - both are offered at The Gynae Centre. All three have a high accuracy rate, are non-invasive, and are safe for mum and baby, and results take the same time to come through. "Both NIPT tests offer a very high level of accuracy, but which you choose ...Panorama and MaterniT21 are both NIPT tests, so we wouldn't recommend doing both. It would be redundant unless there are very specific concerns about your pregnancy. However, it is entirely appropriate to pick one type of NIPT and also to do carrier screening. Also, labs typically have a patient pay price and patient assistance programs to ...Natera has an IP portfolio with over 260 assets, including over 100 in the field of oncology. About Natera Natera is a pioneer and global leader in cell-free DNA testing from a simple blood draw. The mission of the company is to change the management of disease worldwide with a focus on women's health, oncology, and organ health.

Natera measures and reports back fetal fraction. When paternal DNA is available, Natera will report results back with fetal fractions as low as 3.8 percent, but without paternal DNA has a cutoff of 4 percent fetal fraction. ... A study published in Prenatal Diagnosis that looked at the impact of fetal fraction on Sequenom's MaterniT21 ...I got a sample received message 2 days after they drew. They drew on a Monday. Sample received Wednesday, then for some reason I decided to log in to my natera on Sunday and it said review results.. the results were posted Saturday and my doctor released without calling me.Two of the tests currently on the market (MaterniT21™ by Sequenom and Verifi™ by Verinata) use massive parallel ("next generation") sequencing of random DNA fragments in maternal serum, ... The Natera Panorama™ prenatal test may be performed as early as 9 weeks gestation, as compared to the minimum 10 weeks for the initial draw of an ...Hi! I'm trying to register my test kit and when I try, it says they can't find a case that matched the information provided. Does this just mean they haven't received the sample? Yesterday made 72 hours. Is it supposed to be 72 business hours? TIA!Labcorp NIPT Testing vs Natera Panorama. Mymancub. Posted 08-17-20. Hello Mamas! ... but after looking at some others the Maternit21 is just as comprehensive if not more. They do take a little ...Mtnclimber09. • 3 yr. ago. I went through a horrible experience with the NIPT Natera Panorama. I have been very outspoken about their shitty and unreliable algorithm that they use. My MFM HATES Natera Panorama. And I really hate that regular OBs aren't being more upfront about the false negatives and inconclusives.Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, today reported financial results for the first quarter ended March 31, 2023. Recent Strategic and Financial Highlights Generated total revenues of $241.8 million in the first quarter of 2023, compared to $194.1 million in the first quarter of 2022, an increase of 24.5%. Product revenues grew 25.2% over the same period ...kinaski. Feb 7, 2022 at 2:26 PM. Afp is more sensitive for Neural tube defects like Spina bifida. Afp is used for DS screening only in combination with other hormones in your blood. Nipt is far more accurate for trisomies. Don't worry at all!Panorama™ is a blood-based genetic, prenatal screening test of the pregnant person that screens for common chromosomal conditions that affect a baby’s health. Panorama™ uses SNP*-based technology to deliver highly accurate results and unique insights for both singleton and twin pregnancies. Panorama™ can be performed as early as nine ...Natera's clinical trial for non-invasive screening of fetal chromosomal anomalies is funded by the NIH and is being conducted by the leaders in maternal-fetal medicine in the United States. For more information, visit www.natera.com. Quest Diagnostics Contacts: Wendy Bost (Media): 973-520-2800. Dan Haemmerle (Investors): 973-520-2900. Natera, Inc. Gaussian distributions of multiples of the median values were used to estimate modeled FPR and detection rate (DR). For T21, at a 1/300 risk cut-off, DR of screening with all 5 serum markers along with nuchal translucency and nasal bone was 98 % at a 1.2 % FPR. Using a 1/1,000 cut-off, the DR was 99 % with a 2.6 % FPR. Panorama (Natera) is a prenatal test for detecting T21, T18, and T13, as well as select sex chromosome abnormalities. It uses single nucleotide variant technology; results are reported as a risk score. An extended panel tests for 5 microdeletions: 22q deletion

I'm stressed lol. I had my blood draw on Thursday the 22nd. I registered my kit online the same day. I went online to see if there was an update. Didn't see one, so I thought maybe I could message them to get an update. They just replied back that they can't find my case. should I call my doctor?

a. angdgo. Jan 26, 2021 at 1:56 PM. i received your same exact result when I was 19 weeks pregnant, I actually did 2 test through Natera that gave me an atypical result in chromosome 21, I declined the amnio and decided to redo the NIPT through maternit21 and labcorp and my results with them came back normal/low risk!A little over a week - but my case was funny. FL got hit with a hurricane and the lab sort of "lost" my sample for a bit. It was ultimately tracked down but it delayed my results by a few days. I read it's anywhere between 5 and 7 days. Reply reply. spedhead10. •. mine took a week. Reply reply.Natera measures and reports back fetal fraction. When paternal DNA is available, Natera will report results back with fetal fractions as low as 3.8 percent, but without paternal DNA has a cutoff of 4 percent fetal fraction. ... A study published in Prenatal Diagnosis that looked at the impact of fetal fraction on Sequenom's MaterniT21 ...kinaski. Feb 7, 2022 at 2:26 PM. Afp is more sensitive for Neural tube defects like Spina bifida. Afp is used for DS screening only in combination with other hormones in your blood. Nipt is far more accurate for trisomies. Don't worry at all!Here are the stats on inaccurate gender identification with Verifi, MaterniT21, Harmony, and Panorama. This is according to Natera, which makes Panorama, so take it with a grain of salt. My husband and I are only planning on having one and were really hoping for a girl, so we decided to go with Panorama for what we hope are accurate results.Female fetus. We did MaterniT21 + at 9 weeks 4 days and were told 'negative' across the board for everything. Fetal fraction was 10%. At 17 weeks I went for an early anatomy scan and told everything fine except they saw an EIF on baby's heart. I wasn't too worried in light of the negative NIPT (I wish I knew what my risk was).MaterniT21 PLUS Core NO Gender. 452184. Gestational Age > or = 9w: N/A. 451951. MaterniT21 PLUS Core NO Gender. 451942. Test Result. 75980-3.

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About Natera Natera ® is a global leader in cell-free DNA testing. The mission of the company is to change the management of ... MaterniT21 (SQNM) Panorama NIPT volumes show rapid growth among genomic tests 12 Quarters from launch 0 4 8 12 16 20 24 28 32 36 40 44 48 52 56 60 64 68 72 76 60 40 20 0 Test volumes - all products1 Year 600 400 ...Panorama’s SNP-based technology results in the highest fetal sex accuracy of any NIPT in validation studies. Panorama’s SNP-based approach yields the highest commercially available sensitivity for the most common ~3Mb 22q11.2 deletion. For small deletions like 22q11.2, Panorama’s ability to evaluate unique DNA sequences within the region ...MaterniT21 PLUS vs Natera Panorama - comparison. Substantial_Day_5374Panorama has an unethical way of reporting failed tests as automatic high risk of trisomy 18, 13 and triploidy which terrifies people that get that result, and is not accurate. Panorama is SNP, which is thought to be a bit less accurate than WGS. Not sure what MaterniT21 is, the info isn't easy to find. Panorama also makes claims about maternal ...It was recommended over Maternit21 in large part due to cost. We were told Verifi and Maternit21 are essentially the same (accurate results for the same genetic markers). Since our insurance doesn't cover e. I have. The difference is in the accuracy of the results. Panorama is a diagnostic test. It will give you resu.The companies that offer the various NIPS testing (like Panorama, Harmony, MaterniT21, etc…) use techniques that are slightly different from one another, so some of those tests cannot be used in a pregnancy where there is an egg donor involved. Also, although some NIPS tests claim they do well with twins, the test is NOT as powerful in ...For example, MaterniT21 PLUS looks at microdeletions and other abnormalities in a dozen specific chromosomes. MaterniT GENOME screens and detects up to 30% more genetic abnormalities than any other NIPT. It also detects chromosomal aneuploidies missed by other NIPTs, providing earlier awareness and more proactive pregnancy management options.For additional questions regarding cost, Natera’s billing phone number is 877-869-3052 (select 2 to speak with one of our billing experts). Support is available between 7 am – 7 pm Central Time, Monday-Friday, for questions …Oct 19, 2020 · Not to be outdone, soon after verifi entered the market, Sequenom retitled its test as “MaterniT21 Plus,” adding the sex chromosomal aneuploidies. The last to join the competition was Natera with its test, Panorama, distinguishing itself by using a different testing methodology involving single nucleotide polymorphisms or “SNPs”. ….

The Panorama test, developed by Natera, is another prenatal test that analyzes cell-free DNA in the mother’s blood to detect chromosomal abnormalities. It is similar to the MaterniT21 and Harmony tests in its ability to identify trisomy 21, trisomy 18, and trisomy 13.Top-Vegetable7981. MaterniT21 test results posted, then they amended it! Help. No Result / Low Fetal Fraction. Hi folks, I'm losing my mind and need some input. After many issues with fetal fraction and Natera, I stopped lovenox and asprin for one week and did maternit21 test. Last night I get results as negative , male. I was so relieved I ...Proven performance in twin pregnancies. Despite overall limited data on cell-free DNA (cfDNA) testing in twin gestations, MaterniT 21 PLUS has demonstrated high sensitivity …v. NATERA, INC. 9 of an amendment in CareDx’s complaint against Natera, the district court vacated the magistrate judge’s recom-mendation in Natera’s action. The court then adopted the magistrate judge’s recommendation in the Eurofins action but modified the reasoning. The court noted that “lan-Almost 18w, NIPT came back "no result" with Natera. Should I just wait for anatomy scan? Basically title. Thankfully I have an OBGYN appt tomorrow and will be meeting with my actual doctor, so I can ask more questions then. But after initially deciding not to get NIPT done at fertility clinic because they didn't push it, I graduated from ...MaterniT21. GTR Test ID Help Each Test is a specific, orderable test from a particular laboratory, and is assigned a unique GTR accession number. The format is GTR00000001.1, with a leading prefix 'GTR' followed by 8 digits, a period, then 1 or more digits representing the version. When a laboratory updates a registered test, a new version ... Gaussian distributions of multiples of the median values were used to estimate modeled FPR and detection rate (DR). For T21, at a 1/300 risk cut-off, DR of screening with all 5 serum markers along with nuchal translucency and nasal bone was 98 % at a 1.2 % FPR. Using a 1/1,000 cut-off, the DR was 99 % with a 2.6 % FPR. AUSTIN, Texas-(BUSINESS WIRE)- Natera, Inc. (NASDAQ: NTRA), a global leader in cell-free DNA testing, today announced a new study published in Cancer showing the prognostic and predictive utility of Natera's personalized and tumor-informed molecular residual disease (MRD) test, Signatera, to inform adjuvant treatment decisions and monitor for recurrence and therapy response in patients ... Maternit21 vs natera, Orders are routed automatically to our Specialty Testing Services (STS) team who works with a patient’s health plan to determine coverage and need for prior authorization. Email [email protected] or call 1.888.445.5011., For example, MaterniT21 PLUS looks at microdeletions and other abnormalities in a dozen specific chromosomes. MaterniT GENOME screens and detects up to 30% more genetic abnormalities than any other NIPT. It also detects chromosomal aneuploidies missed by other NIPTs, providing earlier awareness and more proactive pregnancy management …, Vistara. Single-Gene NIPT. Vistara is the most comprehensive prenatal single-gene screening test for serious genetic conditions. These conditions, which affect quality of life, could benefit from early intervention and might otherwise go undetected. Vistara tests for 25 serious genetic conditions with a blood draw from the mother., My baby tested high risk for 22q deletion from Natera. I did CVS and it showed fully trisomy 22 in cultured cells and mosaicism in direct sample. I had to do Amnio as well which thankfully came out all clear. Mine was a case of CPM. ... MaterniT21 PLUS vs Natera Panorama - comparison. Substantial_Day_5374, Pregnancy. Si usted habla español, comuníquese con un miembro de nuestro equipo de Every Mom Pledge (Promesa para toda mamá) llamando al 844.799.3243. Utilize Women's Health cost estimator for both pre-pregnancy and pregnancy testing including carrier screening and the genetic health of your baby., P. Benn is a consultant and holds stock options in Natera, Inc. He is also on an Advisory Board for Menarini Biomarkers. A. Rebarber is the President of Carnegie Imaging for Women, PLLC & President of Maternal Fetal Medicine Associates, PLLC. ... Healthcare expenses associated with multiple vs singleton pregnancies in the United …, Horizon carrier screening does not screen for dominant genetic conditions. Horizon carrier screening tests for genetic conditions that happen when both copies of a gene pair have a change. These are called recessive genetic conditions. A carrier of a recessive genetic condition is someone who has a change in one of the genes in a pair., MaterniT21 Results - High risk down syndrome scan and blood test ... ... B, MaterniT21™ PLUS (Sequenom Laboratories, now LabCorp) core test includes T21, T18, T13, and fetal sex aneuploidies. The ... Panorama™ (Natera) is a prenatal test for detecting T21, T18, and T13, as well as select sex chromosome abnormalities. It, It replaces Sequenom's MaterniT21 Plus, which Quest had been offering. At the time, Quest said it had also licensed intellectual property around NIPT from Sequenom and was planning to launch its own test in 2015. QNatal Advanced analyzes cell-free DNA from maternal blood to screen for trisomies 21, 18, and 13., MaterniT21 PLUS vs Natera Panorama - Comparaison No Result / Low Fetal Fraction Si vous êtes aux États-Unis et que vous avez le choix entre NIPT by MaterniT21 (Labcorp) ou Natera Panorama, je choisirais MaterniT21 n'importe quel jour. Je voulais partager mon expérience au cas où cela aiderait quelqu'un à choisir., Natera offers $52.5M for Invitae’s reproductive health screening tests after patent spat. Invitae said in its announcement that the sell-off will help with its ongoing efforts to slash spending ..., MaterniT 21 has quoted me a $900+ out of pocket price based on my insurance and deductive. However, they're saying that they have a 'Moms helping moms tomorrow' program package that the test can cost only $299 if I complete a questionnaire within 30 days of service. Since their quote for my out of pocket was so high, I'm a bit hesitant ..., Could use some help. Apparently, last year (October 2017), I agreed to two different genetic tests (Maternit21 and Panorama). I thought I had only agreed to Maternit21, but that's a different story that I'm working on looking through all of my materials for. In any case, I got a bill from Natera for $800., The width on the NT scan was 1 mm. But the blood work came back at an "increased risk" for Trisomy 21 (1/260 after the test, vs. my 1/303 risk before the test). My Trisomy 13 and 18 risk was still 1/10,000. My doctor said I didn't even need to get the bloodwork at the NT scan since the MaterniT21 is more accurate, and that I should trust those ..., Interested in more writing on the shady dealings of big business? Check out my just-released book with Cambridge University Press and use discount code KUBINEC23 to get 20% off.. My wife and I have been faced with a decision in our pregnancies that has always caused me some consternation: should we take the MaterniT 21 test to see if our baby might have Down's syndrome (trisomy 21) or other ..., Saturday, October 16, 2021. Print Mail Download i. In CareDx (Stanford U.) v. Natera Civ. Action No. 19-0567-CFC-CJB Consolidated (Sept. 28, 2021, D. Delaware), Judge Connolly ruled that the ..., m. Mymancub. Posted 08-17-20. Hello Mamas! Has anyone gotten Labcorp NIPT testing done instead of the Natera Panorama or others? My OB-GYN suggested the Labcorp one is more thorough than the ... , Yesterday (16 weeks preg) I received a second NIPT result of "Not Reportable - testing for this sample was performed. Due to technical or sample related issues, data failed to meet quality standards for interpretation" for the Materniti21 test from lab corp. First Test taken at 11wk3 days, Second Test taken at 13wk2 days, 28 yr old, lower ..., The cost of the procedure can range from several hundred dollars to over $1,000. The cost of the genetic testing has a similar range, though discounted cash pay prices may be available. This test is often covered by insurance, particularly if there are factors that put the pregnancy at a high risk for genetic or chromosome conditions., According to Natera, maker of Panorama, ... MaterniT21 claims a 99.4% accuracy rate for fetal gender -- or 6 errors per 1,000 tests. Again using MaterniT21's figure of having performed 250,000 tests, that's around 1,500 cases of reporting the wrong fetal sex. And while those parents were no doubt shocked to deliver a baby that was not the ..., m. Mymancub. Posted 08-17-20. Hello Mamas! Has anyone gotten Labcorp NIPT testing done instead of the Natera Panorama or others? My OB-GYN suggested the Labcorp one is more thorough than the ..., I didn't do NIPT, only Nuchal Translucency, (and had also done PGS) but what I was told was that as the cells divide and grow that abnormalities may occur. I did PGT testing and still did the NIPT testing. My OB said that sometimes during PGT testing the embryo can get damaged and cause issues (rare but can happen)., Took the MaterniT21 test at 10 weeks and was already slightly skeptical of the results. The first results said "congrats on the singleton pregnancy, it's a boy," and we had to say "uhh, no, there's twins in there." They still had the blood sample so went back and re-tested. Alongside the everything-is-normal results, they told us "Based on the ..., Antenatal DNA Screening - Sequenca Genetics. There are 3 available tests, MaterniT21, which is the core test, MaterniT21 Plus, and MaterniT Genome. We will take you through an online pretest education session prior to testing so you understand the differences between the tests and can make the right choice for you. We take your blood test from ..., Jan 7, 2022 at 8:16 AM. This is the second baby I’ve got the Maternit21 test with. LabCorp is located in the same building as my OB so she referred me there. The test cost me $150 out of pocket and I got my results back in five days. LabCorp is open on the holidays so I had no delay from Christmas or New Years., Case Summary. On December 20, 2022, Natera, Inc. ("Natera" or "Plaintiff"), represented by Anthony D. Raucci, Derek J. Fahnestock, and Jack B. Blumenfeld of Morris, Nichols, Arsht & Tunnell LLP, filed an intellectual property lawsuit against Inivata, Inc. and Inivata Ltd. (collectively, "Inivata" or "Defendants"), seeking ..., m. Mymancub. Posted 08-17-20. Hello Mamas! Has anyone gotten Labcorp NIPT testing done instead of the Natera Panorama or others? My OB-GYN suggested the Labcorp one is more thorough than the ... , Jan 15, 2015 at 11:06 AM. I had both. My specialist required NT- had abnormalities pointing to genetic problems, so did maternit21 to get more info. Did require insurance pre-approval. I got results back in about 10 business days (my cells were slow to grow) and at least what they test for came back normal., Like many of you looking at this page, we had two low fetal fraction Natera draws. We had our first Natera draw at 9+6. Ten days later, it comes back inconclusive with a ff of 2.3%. Our OB recommended we do another draw immediately, though her nurse indicated some hesitation because we were only at 11+2. My wife does have a BMI of 34, but the ..., FRONTIER MFG SELECT INFRASTRUCTURE FUND SERVICE CLASS- Performance charts including intraday, historical charts and prices and keydata. Indices Commodities Currencies Stocks, With my first we took a panorama test and with this one the clinic is suggesting MaterniT21 (I am assuming they have a tie up). Anyone experienced with both…, MemphisMommy2012. Jul 4, 2012 at 9:17 AM. @bman2075, The M21 is extremely accurate (over 99%). The purpose of it is to give you the same results that you'd get from the amnio or CVS without the risks. There's no need to get the amnio if your already done the M21. Hopefully, your results will come in soon.